In premature ovarian failure, ovarian function is impaired before the age of 40 by stopping
ovulation and producing the hormone estrogen.
Although the symptoms of premature ovarian failure and menopause are the same,but the two
are quite different.
People with premature ovarian failure may have irregular periods for years and may even
become pregnant.
However, women who have premature menopause have stopped menstruating and can not get
pregnant.
Causes of POF:
-Genetic factors (chromosomal problems) like Turner syndrome and fragile X syndrome)
-Harmful factors to the ovaries such as surgery
chemotherapy and radiotherapy
-Autoimmune diseases
-Thyroid diseases
-Unknown reasons
If ovarian failure occurs at the younger ages, genetic factors are more likely to be present.
Exposure to toxins such as pesticides as well as some viruses can also cause premature
ovarian failure.
Symptoms and complications of POF include the following:
-Irregular menstruation or temporary interruption of menstruation.
-Flushing
-Night sweating
-Vaginal dryness
-Lack of focus
-Dry eyes
-Sleep disorders
-Osteoporosis
-Mood disorders and depression or anxiety
-Decreased sexual desire
-Heart disease
Diagnosis of premature ovarian failure:
Pelvic and ovarian ultrasound
Hormonal evaluation
Doing karyotyp ( a kind of genetic test) to find genetic defects
The treatment of premature ovarian failure will be based on the patient's chief complaint.